Nasa Technology Reveals
Bacteria's Role in Breast Cancer
Using planetary protection techniques that ensure Nasa
spacecraft do not contaminate other worlds, researchers, including one of
Indian-origin, have found a link between bacteria in breast ductal fluid and
breast cancer.
The breast ductal system contains the glands that produce milk
and naturally secretes a substance called "nipple aspirate fluid".
For the study, the researchers at Nasa's Jet Propulsion
Laboratory, Pasadena, California, employed the same sequencing and analysis
methods used for examining bacteria in spacecraft assembly rooms.
"We applied these planetary protection techniques in the
first-ever study of microorganisms in human breast ductal fluid," said
Parag Vaishampayan, scientist in biotechnology and planetary protection at JPL.
The researchers found differences between the ductal fluid
bacteria found in women who have experienced breast cancer, and the bacteria
present in those who have not.
The findings were published in the online journal Scientific
Reports.
The research team found that the community of microorganisms in
breast ductal fluid differed significantly between two groups - 23 healthy
women and 25 women who had a history of breast cancer and had gone through
treatment.
It was then analysed with next-generation genomic sequencing,
which has also been used for examining bacteria in Nasa spacecraft
assembly facilities.
For the study, Nasa scientists collaborated with cancer
researchers from different institutions.
"Collaboration between JPL space technology experts and
medical researchers will continue to propel groundbreaking discoveries,"
Vaishampayan, who earned in PhD from University of Pune in Maharashtra, said.
"This publication represents a success for JPL's Medical
Engineering Forum Initiative, which focuses on applying Nasa technology for
medical needs here on Earth," JPL's Leon Alkalai, who is spearheading the
initiative said in a statement.
Though the study found a correlation between specific species of
bacteria and women who have gone through breast cancer treatment, the cause of
the bacterial population difference is unclear.
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